Screening for Type 2 Diabetes Mellitus to Prevent Vascular Complications

Summary

There is fair evidence to recommend screening adults with hypertension for type 2 diabetes to reduce the incidence of cardiovascular (CV) events and mortality (Grade B recommendation).

There is fair evidence to recommend screening adults with hyperlipidemia for type 2 diabetes to reduce the incidence of CV events and mortality (Grade B recommendation).

There is good evidence to recommend treatment of overweight* individuals with impaired glucose tolerance (IGT) with lifestyle interventions to reduce the incidence of diabetes progression (Grade B recommendation).

There is sufficient evidence to recommend treatment of overweight* indidivuals with IGT with metformin or acarbose to reduce the incidence of diabetes progression (Grade I recommendation).

There is fair evidence to recommend treatment of overweight* individuals with IGT with acarbose to prevent cardiovascular outcomes and hypertension (Grade B recommendation).

*Body mass index (BMI, kg/m2) > 25 or > 22 in individuals of Asian descent